55 Francisco Street #300, San Francisco, California 94133
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At HRC Fertility, we know that reaching out for help can feel like a big step. Whether you are just starting to ask questions or you have been trying to grow your family for some time, our team in San Francisco is here to listen, explain your options, and offer evidence-based care that fits your life.
Your first visit is a chance to share your story, review your medical history, and talk through possible next steps with a fertility specialist. There is no pressure to decide on treatment that day. Our goal is to give you clear information, answer your questions, and help you feel more confident about where to go from here.
During your initial appointment, you will meet with a fertility specialist to review your health history, discuss any prior testing or treatments, and talk about your goals. We may recommend basic bloodwork or imaging to better understand your reproductive health. You will leave with a clearer sense of your options and what a personalized plan could look like for you.


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Our reproductive endocrinologists provide care to patients throughout the San Francisco Bay Area, offering evaluations, treatment planning, and ongoing support. To see all HRC Fertility physicians and find the right fit for you, visit our full physician directory.
We encourage you to explore our physician profiles to learn more about each provider’s training, clinical interests, and approach to patient care. Finding a doctor you feel comfortable with is an important part of this process, and our team is here to help you make that connection.
At HRC Fertility, your care is led by physicians with advanced training in reproductive endocrinology and infertility, supported by an experienced team of nurses, embryologists, and patient coordinators. Together, we focus on understanding your medical history, your goals, and your comfort level with different treatment options.
Our physicians stay current with developments in fertility medicine through ongoing education and research involvement. This allows us to offer treatment plans that reflect both established best practices and emerging data, while always centering your safety and preferences.
HRC Fertility uses RI Witness, an electronic witnessing system designed to help prevent sample mix-ups in the laboratory. The technology uses radiofrequency identification (RFID) tags to track eggs, sperm, and embryos at each step, adding another layer of verification alongside our existing safety checks.
With RI Witness, every dish and tube is monitored as it moves through the lab, and the system alerts staff if anything does not match the expected patient identity. This supports a controlled environment for your reproductive materials and reflects our commitment to careful, detail-oriented care.


Needle-free IVF, developed by our own Dr. Rachel Mandelbaum, is designed to lessen the anxiety and discomfort of frequent injections some of our patients experience. The approach uses a simple technology that decreases the number of injections directly into the skin, while using established IVF protocols. Your physician will review whether this method is appropriate for you and explain how it compares to standard injections.

Egg freezing allows patients to preserve eggs for potential use later, which may be helpful for personal, medical, or professional reasons. At HRC Fertility, your care team will explain the stimulation process, egg retrieval, and storage, as well as how frozen eggs can be used in the future. For more details about our approach, visit our egg freezing page.

Intrauterine insemination (IUI) is a procedure in which prepared sperm is placed directly into the uterus around the time of ovulation. IUI may be recommended in certain situations, such as mild male factor infertility, unexplained infertility, or for single parents and some LGBTQIA+ patients using donor sperm. Your physician will discuss whether IUI is a reasonable option based on your specific circumstances.

HRC Fertility participates in selected research and clinical studies that aim to improve understanding of fertility treatments and outcomes. When appropriate, eligible patients may be invited to consider taking part. Participation is always optional, and your physician will explain any study details, potential risks, and alternatives so you can make an informed decision.

Intracytoplasmic Sperm Injection (ICSI) is a specialized IVF procedure used for severe male infertility, where an embryologist injects a single sperm directly into an egg using a fine glass needle. This method is recommended for cases with poor fertilization history in standard IVF, or issues such as low sperm count, poor motility, abnormal morphology, or obstructions like vasectomy. While highly effective, ICSI involves more handling and carries a slight risk (less than 2%) of egg damage. It offers hope to couples facing unique fertility challenges by bypassing traditional barriers to conception.

HRC Fertility offers comprehensive support for patients who may use donor eggs, donor sperm, donor embryos, or gestational carriers as part of their family-building plans. Our team coordinates medical care with third-party agencies and other professionals to help keep the process organized and transparent.
We also work closely with LGBTQIA+ patients and families, providing care plans that reflect their specific goals and circumstances. From initial counseling and testing to treatment and pregnancy care coordination, we aim to create an affirming environment at every step.

HRC Fertility offers structured treatment packages designed to bring together common services in a clear, predictable way. These packages can help simplify planning and may make it easier to understand the typical steps and costs involved in your care.
We also make it easy for you to give the gift of fertility services to a loved one. Right now, we are offering a special promotion. If you purchase a gift voucher, HRC Fertility will match up to $2,000 for your loved one looking to build their family. Please check our special offers page linked below for more information on this promotion and other promotions that we are currently offering.

Our media and blog library includes patient-focused articles, updates from our physicians, and educational pieces about fertility testing and treatment. These resources are designed to help you understand your options and feel more prepared for conversations with your care team.
You can explore topics ranging from IVF and egg freezing to emotional support and financial planning. While online information is not a substitute for medical advice, it can be a helpful starting point as you think about questions to bring to your appointments.

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6:00 - 8:00 PM

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