55 Francisco Street, #300, San Francisco, California, 94133
HRC Fertility is here to help if you're suffering recurrent pregnancy loss and searching for answers. Our caring team of specialists uses advanced tools and new treatments to find out what's causing the problem and create solutions just for you. We focus on proven methods and the latest technology, making sure you get the support you need during your journey with us.

Recurrent pregnancy loss can be heartbreaking and confusing. At HRC Fertility, we offer focused care for people who have had repeated miscarriages, combining advanced testing with careful listening.
Our goal is to look for clear answers, explain what we find in simple terms, and build a plan that respects your history, your health, and your hopes for the future.
When you come to us for recurrent pregnancy loss care, you are seen by fertility specialists who manage these complex cases every day. We bring together medical expertise, up-to-date research, and emotional support so you do not have to face the next steps alone.
Recurrent pregnancy loss is usually defined as having two or more miscarriages. These losses can happen very early, sometimes before a heartbeat is seen, or later in the first or second trimester. While one miscarriage is common and often due to chance, repeated losses may point to an underlying medical, genetic, or anatomical issue that deserves a closer look.
Common causes of recurrent pregnancy loss include chromosomal problems in the embryo, structural differences in the uterus, blood clotting disorders, hormonal or thyroid issues, and certain immune conditions. In some cases, no clear cause is found even after a careful workup, but understanding what has been ruled out can still guide safer, more informed treatment choices.
Many people are told that miscarriage is always random and that nothing can be done. While some losses are due to chance, repeated miscarriages are more likely to have an underlying cause. A full evaluation can sometimes identify treatable factors, such as a uterine septum, a blood clotting disorder, or a hormonal imbalance. Even when testing does not show a single clear reason, the information gathered can still shape a safer plan for future pregnancies.

These numbers can feel overwhelming, but they also show that you are not alone and that many people with a history of recurrent loss do go on to have successful pregnancies with the right support.

HRC Fertility’s recurrent pregnancy loss program is designed for patients who want a careful, step-by-step plan instead of one-size-fits-all advice. From your first visit, we review your full medical and pregnancy history, past test results, and any treatments you have already tried. We then recommend targeted testing and a treatment plan that fits your specific situation, rather than repeating the same approach that has not worked before.
Your care team may include reproductive endocrinologists, nurses, genetic counselors, and other specialists as needed. We coordinate your testing and follow-up visits, explain each step in plain language, and check in regularly so you understand what we are looking for and why. This comprehensive approach helps us support both your physical health and your emotional well-being.
A thorough evaluation is the first step in understanding recurrent pregnancy loss. Your provider may recommend:
The exact tests are chosen based on your history and prior results, so you are not asked to repeat studies that are not helpful.
Once testing is complete, your care team will discuss treatment options that match your specific findings. These may include:
Your plan is designed to be realistic, evidence-based, and aligned with your goals and values.
Recurrent pregnancy loss can have many overlapping causes, and in some cases no single reason is found. At HRC Fertility, we follow an evidence-based approach that focuses on conditions known to increase the risk of miscarriage, such as chromosomal abnormalities, uterine differences, blood clotting disorders, hormonal or thyroid problems, and certain immune issues. We avoid unproven tests and treatments that add cost and stress without clear benefit, and instead focus on options supported by research and clinical experience.
Chromosomal differences are one of the most common reasons for miscarriage. In many cases, the embryo has too many or too few chromosomes, which usually happens by chance when the egg and sperm join. This can lead to early pregnancy loss, even when both partners are healthy. For some couples, especially those with repeated losses, testing may show a balanced translocation or other inherited chromosomal change in one partner. While this person is often healthy, the change can increase the chance of embryos with the wrong number of chromosomes.
Uterine differences, such as a septum, fibroids that distort the cavity, or scar tissue inside the uterus, can make it harder for an embryo to implant and grow. Imaging tests like ultrasound, saline sonogram, or hysterosalpingogram help your doctor see the shape of the uterus and the lining. When a structural issue is found and thought to affect pregnancy, a minor surgical procedure may be recommended to improve the space where a pregnancy develops.
Hormones and overall health play an important role in early pregnancy. Your care team may look for:
When these conditions are found, treatment may include medication, lifestyle changes, or hormone support around the time of conception and early pregnancy.
Some inherited or acquired blood clotting disorders can increase the risk of pregnancy complications, including miscarriage in certain situations. Your provider may order specific blood tests if your history suggests this could be a factor. When a relevant condition is confirmed, treatment during pregnancy may include low-dose aspirin, blood thinners, or closer monitoring, based on current guidelines and your overall health.
Immune conditions, such as antiphospholipid syndrome, and other medical issues can also contribute to recurrent pregnancy loss. Your doctor will decide which tests are appropriate based on your symptoms, history, and prior results. We focus on conditions where research shows that treatment can make a meaningful difference, and we avoid unproven immune therapies that have not been shown to improve outcomes.
In some cases, even after a complete evaluation, no single clear cause is identified. This can feel frustrating, but it does not mean there is no hope. Many people in this situation still have a good chance of a future successful pregnancy. Your care team will talk with you about what has been ruled out, how your age and history affect your chances, and what monitoring or treatment might still be helpful moving forward.
Repeated pregnancy loss affects more than your physical health. It can bring grief, anxiety, and fear about trying again.
At HRC Fertility, we recognize the emotional weight of these experiences and build support into your care. Our team takes time to listen, answer questions, and move at a pace that feels manageable for you.
When needed, we can connect you with counselors, support groups, and other resources that focus on fertility and pregnancy loss. We also work closely with your other healthcare providers, such as your primary care doctor or obstetrician, to help coordinate care before, during, and after pregnancy.
Emotional support is an important part of recurrent pregnancy loss care. Many patients benefit from talking with a mental health professional who understands fertility concerns, joining a support group, or including partners and family members in visits. Our team can share resources, provide letters or information for your therapist if needed, and make space during appointments to talk about how you are coping, not just about test results.

Many people are evaluated after two miscarriages, especially if they are older than 35 or have other health concerns. You can also ask for an earlier visit if you feel worried or if your doctor has specific concerns about your history. An initial consultation does not mean you must start treatment right away; it is a chance to ask questions and learn about your options.
For your first appointment, it helps to bring records from past pregnancies, including ultrasound reports, lab results, and any procedure notes you may have. If you have had genetic testing, blood work, or surgery related to fertility, please bring those reports as well. Writing down your questions ahead of time can also make it easier to remember what you want to discuss.
No fertility clinic can guarantee a pregnancy or a specific outcome. What we can offer is a careful, evidence-based evaluation, clear explanations of your chances based on your age and history, and a treatment plan that aims to improve your odds where possible. We will be honest about what is known, what is uncertain, and what choices you have moving forward.
Coverage for recurrent pregnancy loss evaluation and treatment varies by insurance plan. Some tests and visits may be covered, while others may not. Our financial counselors can review your benefits, explain expected costs, and discuss payment options or packages that may be available so you can plan ahead.